Gene fusions, arising from chromosomal rearrangements or aberrant splicing events, generate chimeric transcripts that can drive oncogenesis through novel protein products or altered gene regulation.

Whole-genome bisulfite sequencing (WGBS) provides multiple molecular information layers including methylation, copy number variations (CNVs), single nucleotide variants (SNVs), and fragmentome ...

Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that ...

A team of scientists from the Barbara Ann Karmanos Cancer Institute, Wayne State University and institutions across the U.S.

The National Biomarker Centre says the extra money will make a "huge difference" to its work.

Researchers are calling for the application of locally driven strategies, supported by stronger regional evidence, to improve early cancer detection and precise care.

Angus reports on the basic research, clinical science, and drug development that may transform survival and quality of life for patients, as well as developments affecting the cancer community. You ...

A new light-based sensor can spot incredibly tiny amounts of cancer biomarkers in blood, raising the possibility of earlier and simpler cancer detection. The technology merges DNA nanotechnology, ...

More than 150 lung cancer researchers, clinicians and patient advocates from around the country gathered at Fred Hutch last ...

Some claim the new multi-cancer detection tests will “revolutionize” cancer screening. Others fear the “worried well” will succumb to slick marketing and subpar tests and overwhelm both primary care ...